Anti-tumour effect of EF-2001 on Meth-A fibrosarcom in mice
A suppression trend was observed in the EF-2001 group in contrast to the control group from around the 13th day following transplant, with a marked decrease in the size of the tumour from the 15th day.
Anti-tumour effect of EF-2001 on Sarcoma-180 in mice
The size of the tumour (mm2) in the EF-2001 group markedly decreased compared to the control group throughout the measurement period from the 2nd day of administration (the 4th day after tumour transplant), and a notable tumour growth inhibitory effect was observed.
Lymphocyte / polymorphonuclear leukocyte increase (L/P activity) effect of EF-2001 in the peripheral blood of mice
The control group showed a gradual increase, while the EF-2001 group showed a rapid increase, with a significantly (P＜0.5) higher L/P than the control group at every point and a particularly pronounced significant difference on the 14th day.
